ORGANIC NITRATES Examples Nitroglycerine, amyl nitrite, isosorbide dinitrate, isosorbide-5-mononitrate, erythrityl tetranitrate, pentaerythritol tetrani-trate. Physical Appearance Organic nitrates are polyol esters of nitric acid.* Amyl nitrite is a highly volatile liquid, while low molecular mass nitrates such as nitroglycerine** are moderately volatile, oily liquids, and high molecular mass nitrate esters such as erythrityl tetranitrate are solids. All organic nitrates are capable of denitration (i.e. they release nitric oxide), and are collectively termed nitrovaso-dilators. Uses Treatment of · Angina pectoris (and some cases of myocardial infarction). · Prinzmetal’s angina. · Congestive heart failure. Toxicokinetics ■■ ...
Marking Nut Botanical Name Semecarpus anacardium. Physical Appearance ■■ This tree belonging to family Anacardiaceae grows well inmany parts of the country, and bears oblong leaves rounded Toxic Principles ■■ Semecarpol ■■ Bhilawanol. Clinical Features · Skin contact with the acrid juice results in irritation, inflam-mation, vesication, and ulceration. · Ingestion produces GI distress with blister formation in and around the mouth. Severe poisoning results in vomiting, abdominal pain, diarrhoea, hypotension, tachycardia, delirium, and coma. Pupils may be dilated. Usual Fatal Dose · About 5 to 8 seeds, or 10 grams. Treatment · Wash contaminated skin with soap and water, and treat lesions with help of a dermatologist. · ...
Mayapple (May Apple) Other Common Names · American Mandrake. Botanical Name · Podophyllum peltatum, Podophyllum hexandrum Physical Appearance · This plant belonging to family Podophylaceae grows well in the hilly regions of Sikkim, Uttar Pradesh, Punjab, Himachal Pradesh, and Kashmir. · It is a flowering herb with a creeping root stock with deeply lobed leaves having toothed margins ( Fig 10.15 ). · Flowers are usually solitary, cup-shaped, and white or pink in colour. · Fruits a...
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