Croton Botanical Name Croton tiglium Physical Appearance ■■ This plant belonging to family Euphorbiaceae grows well in Assam, Bengal, and the Western Ghats. ■■ It is a small evergreen tree with ovate or elliptical leaves which are narrow-pointed, toothed, and 2 to 4 inches long, varying in colour from metallic green to bronze, orange, or yellowish ( Fig 10.10 ). ■■ Seeds are oval, smooth, 1 to 2 cm long, and brownish in colour ( Fig 10.11 ). Uses The seeds, oil, and root extract are used as a drastic purgative in folk medicine. Toxic Part Stem, leaves, seeds. Toxic Principles ■■ Crotin (toxalbumen). ■■ Crotonoside (glycoside). Clinical Features · Plants in this family contain irritant diterpene esters that are strongly irritating. Rubbing the latex of these plants to the face, or chewing on the stem may result in erythema, swelling, and blistering. Initial symptoms of reddening and swelling occur in 2 to 8 hours...
Mayapple (May Apple) Other Common Names · American Mandrake. Botanical Name · Podophyllum peltatum, Podophyllum hexandrum Physical Appearance · This plant belonging to family Podophylaceae grows well in the hilly regions of Sikkim, Uttar Pradesh, Punjab, Himachal Pradesh, and Kashmir. · It is a flowering herb with a creeping root stock with deeply lobed leaves having toothed margins ( Fig 10.15 ). · Flowers are usually solitary, cup-shaped, and white or pink in colour. · Fruits a...
ORGANIC NITRATES Examples Nitroglycerine, amyl nitrite, isosorbide dinitrate, isosorbide-5-mononitrate, erythrityl tetranitrate, pentaerythritol tetrani-trate. Physical Appearance Organic nitrates are polyol esters of nitric acid.* Amyl nitrite is a highly volatile liquid, while low molecular mass nitrates such as nitroglycerine** are moderately volatile, oily liquids, and high molecular mass nitrate esters such as erythrityl tetranitrate are solids. All organic nitrates are capable of denitration (i.e. they release nitric oxide), and are collectively termed nitrovaso-dilators. Uses Treatment of · Angina pectoris (and some cases of myocardial infarction). · Prinzmetal’s angina. · Congestive heart failure. Toxicokinetics ■■ ...
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